Liverpool University Hospitals NHS Foundation Trust has been nominated for admission to the Freedom Roll of Associations and Institutions.
Emergency service colleagues at Merseyside Fire and Rescue have also been nominated for the honour.
The nominations will be among those considered at an Extraordinary General Meeting of Liverpool City Council in January and, if approved, will be followed by individual ceremonies later this year.
Steve Warburton, Chief Executive of Liverpool University Hospitals NHS Foundation Trust, said: “It is an incredible honour to receive the Freedom of the City of Liverpool. This is a testament to the hard work, dedication and service of each of our 12,000 staff and volunteers committed to delivering outstanding healthcare to our patients.
“Our staff at Aintree, Broadgreen and Royal Liverpool Hospitals and the Liverpool University Dental Hospital, many of whom are proud Liverpudlians, strive every day to serve this great city and its people. We deeply appreciate this tribute of being awarded the city’s highest civic honour.”
Joe Anderson, Mayor of Liverpool, said: “The people and organisations that have been chosen for Freedom of Liverpool and Citizen of Honour awards have made a tremendous positive contribution to life in the city over many years. We owe a huge debt of gratitude to the hard-working and committed staff in our hospitals, and our firefighters, for helping save lives every day.”